验证数据展示
Planning an IHC experiment? We recommend our IHCeasy IBA1 Ready-To-Use IHC Kit. IBA1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66827-1-Ig
发表文章中的应用
| IF | See 1 publications below |
产品信息
CL594-66827 targets IBA1 in IF applications and shows reactivity with human samples.
| 经测试应用 | Application Description |
| 文献引用应用 | IF |
| 经测试反应性 | human |
| 文献引用反应性 | mouse |
| 免疫原 | IBA1 fusion protein Ag28236 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | allograft inflammatory factor 1 |
| 别名 | AIF1, G1, allograft inflammatory factor 1, AIF-1, AIF 1 |
| 计算分子量 | 17 kDa |
| GenBank蛋白编号 | BC009474 |
| 基因名称 | IBA1 |
| Gene ID (NCBI) | 199 |
| ENSEMBL Gene ID | ENSG00000204472 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P55008 |
| 储存缓冲液 | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IBA1 is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Expression of IBA1 is up-regulated in activated microglia following facial nerve axotomy, ischemia, and several brain diseases, thereby implicating it in the activated phenotypes of microglia.