IFT57 Antibody 10 Publications

Rabbit Polyclonal| Catalog number: 11083-1-AP

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse, rat, dog

Positive WB detected in:
mouse retina tissue, HEK-293 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human prostate cancer tissue, human pancreas tissue, human prostate cancer tissue

Positive IF detected in:
MDCK cells

Recommended dilution:
WB : 1:200-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
intraflagellar transport 57 homolog (Chlamydomonas)

Calculated molecular weight:
49 kDa

Observed molecular weight:
49 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IFT57

Synonyms
DERP8, ESRRBL1, FLJ10147, HIP1 interacting protein, HIPPI, IFT57, MHS4R2
Background

IFT57, also named as DERP8, ESRRBL1, HIPPI and MHS4R2, belongs to the IFT57 family. It is required for the formation of cilia. IFT57 plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. It is a component of IFT complex B which composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20. In contrast to BBS proteins, IFT57 and IFT88 is found in almost every cilium.(PMID:22072986)


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