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  • Featured Product
  • KD/KO Validated

KIF5B Recombinant antibody, PBS Only

KIF5B Recombinant Antibody for WB,Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse, rat

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B18

Cat No : 82485-1-PBS

Print datasheet

Synonyms

KIF5B, Kinesin 1 heavy chain, kinesin family member 5B, KINH, KNS, KNS1, Ubiquitous kinesin heavy chain, UKHC

验证数据展示

  • WB analysis using 82485-1-RR (same clone as 82485-1-PBS)

    WB analysis using 82485-1-RR (same clone as 82485-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82485-1-RR (KIF5B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82485-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 82485-1-RR (same clone as 82485-1-PBS)

    WB analysis of HeLa using 82485-1-RR (same clone as 82485-1-PBS)

    WB result of KIF5B antibody (82485-1-RR; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-KIF5B transfected HeLa cells. This data was developed using the same antibody clone with 82485-1-PBS in a different storage buffer formulation.

产品信息

82485-1-PBS targets KIF5B in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Applications WB,Indirect ELISA
Tested Reactivity Human, mouse, rat
Immunogen KIF5B fusion protein Ag16250 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name kinesin family member 5B
Synonyms KIF5B, Kinesin 1 heavy chain, kinesin family member 5B, KINH, KNS, KNS1, Ubiquitous kinesin heavy chain, UKHC
Calculated Molecular Weight 963 aa, 110 kDa
Observed Molecular Weight 110-120 kDa
GenBank Accession NumberBC126279
Gene Symbol KIF5B
Gene ID (NCBI) 3799
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP33176
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

KIF5B, also known as KINH, KNS1, belongs to the Kinesin-1 family. KIF5B contains three structural domains: a globular N-terminal motor domain, a central alpha-helical rod domain, and a globular C-terminal domain. During the G2 phase of the cell cycle in a BICD2-dependent manner, KIF5B antagonizes the dynein function and drives the separation of nuclei and centrosomes (PMID: 20386726). KIF5B drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (KIF5B:24088571).