LGR5 Polyclonal antibody
LGR5 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse brain tissue, rat brain tissue |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
30007-1-AP targets LGR5 in WB, ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Applications | WB, ELISA |
Tested Reactivity | Human, Mouse, Rat |
Immunogen | LGR5 fusion protein Ag31625 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | leucine-rich repeat-containing G protein-coupled receptor 5 |
Synonyms | FEX, G protein coupled receptor 49, G protein coupled receptor 67, GPR49, GPR67, GRP49, HG38, LGR5 |
Calculated Molecular Weight | 907 aa, 100 kDa |
Observed Molecular Weight | 110 kDa |
GenBank Accession Number | BC096324 |
Gene Symbol | LGR5 |
Gene ID (NCBI) | 8549 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O75473 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5 gene. It is a member of GPCR class A receptor proteins. R-spondin proteins are the biological ligands of LGR5. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells in certain tissues.LGR5 is crucial during embryogenesis as LGR null studies in mice incurred 100% neonatal mortality accompanied by several craniofacial distortions such as ankyloglossia and gastrointestinal dilation (PMID: 9642114, 16575208, 525477).
实验方案
Product Specific Protocols | |
---|---|
WB protocol for LGR5 antibody 30007-1-AP | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |