NRG4 Polyclonal antibody

NRG4 Polyclonal Antibody for ELISA
Cat No. 11206-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

ELISA

Pro-neuregulin-4, membrane-bound isoform, Pro NRG4, NRG 4, Neuregulin-4, neuregulin 4

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size: 

-/ -


产品信息

11206-1-AP targets NRG4 in ELISA applications and shows reactivity with human, mouse samples.

Tested Applications ELISA Application Description
Tested Reactivity human, mouse
Immunogen NRG4 fusion protein Ag1697 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name neuregulin 4
Synonyms Pro-neuregulin-4, membrane-bound isoform, Pro NRG4, NRG 4, Neuregulin-4, neuregulin 4
Calculated Molecular Weight 13 kDa
GenBank Accession NumberBC017568
Gene Symbol NRG4
Gene ID (NCBI) 145957
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8WWG1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is expressed in multiple organs with the highest expression levels in brown adipose tissue. Neuregulin 4 is a secreted adipokine recently identified as playing an important role in modulating systemic energy metabolism and in the development of metabolic disorders in rodent and human obesity, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Nrg4 attenuates hepatic lipogenic signaling and preserves glucose and lipid homeostasis in obesity.

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