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  • KD/KO Validated

NUAK2 Polyclonal antibody

NUAK2 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA and More (3)

Conjugate

Unconjugated

Cat no : 11592-1-AP

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Synonyms

SNARK, OMPHK2, NUAK family SNF1-like kinase 2, NUAK 2, EC:2.7.11.1



产品信息

11592-1-AP targets NUAK2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA Application Description
Cited ApplicationsWB, IHC, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen NUAK2 fusion protein Ag2031 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name NUAK family, SNF1-like kinase, 2
Synonyms SNARK, OMPHK2, NUAK family SNF1-like kinase 2, NUAK 2, EC:2.7.11.1
Calculated Molecular Weight 628 aa, 70 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC017306
Gene Symbol NUAK2
Gene ID (NCBI) 81788
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H093
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NUAK2(NUAK family SNF1-like kinase 2) is also named as OMPHK2, SNARK and belongs to the SNF1 subfamily. The function of NUAK2 is partly dependent on anti-apoptotic properties against apoptosis induced by death ligand and NUAK2 also has effects on the migration of cancer cells as speculated from studies on myosin filaments and cytoskeleton organization in normal cells(PMID:21911917). Western blot analysis detected NUAK2 expressed in cancer cell lines of diverse tissue origin(PMID:12409306).

发表文章

SpeciesApplicationTitle
humanWB,IHC

Proc Natl Acad Sci U S A

AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.

Authors - Namiki Takeshi T
humanWB, IF

Cancer Res

NUAK2 amplification coupled with PTEN deficiency promote melanoma development via CDK activation.

Authors - Takeshi Namiki
  • KD Validated
humanWB

Diabetologia

Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes.

Authors - Rune A A
  • KD Validated
humanWB, IF

Ann Clin Biochem

Sucrose non-fermenting AMPK related kinase/Pentraxin 3 and DNA damage axis: a gateway to cardiovascular disease in systemic lupus erythematosus among Egyptian patients.

Authors - Doaa Hussein Zineldeen