STIM1 Recombinant antibody, PBS Only
STIM1 Recombinant Antibody for WB,Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse, rat
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1B13
验证数据展示
产品信息
81156-1-PBS targets STIM1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| Tested Applications | WB,Indirect ELISA |
| Tested Reactivity | Human, mouse, rat |
| Immunogen | STIM1 fusion protein Ag2140 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | stromal interaction molecule 1 |
| Synonyms | D11S4896E, GOK, STIM1, stromal interaction molecule 1 |
| Calculated Molecular Weight | 685 aa, 77 kDa |
| Observed Molecular Weight | 77 kDa |
| GenBank Accession Number | BC021300 |
| Gene Symbol | STIM1 |
| Gene ID (NCBI) | 6786 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q13586 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
STIM1, also named as GOK, is an ER Ca2+ sensor. Upon Ca2+ store depletion, STIM1 clusters at ER-plasma membrane junctions where it interacts with and gates Ca2+-permeable Orai1 ion channels. STIM1 is implicated in tumor growth suppression and stromal-haematopoietic cell interactions. Defacts in STIM1 gene can cause immune dysfunction with impaired T-cell activation. STIM1 can inhibit L-type voltage-gated Ca(2+) channels in neurons. Temperature is an important regulator of STIM1 function.
