VDAC1/Porin Antibody 27 Publications

Rabbit Polyclonal| Catalog number: 10866-1-AP

Featured Product KD/KO validated

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Species specificity:
human, mouse, rat, Pieris rapae

Positive WB detected in:
HEK-293 cells, DU 145 cells, HeLa cells, HL-60 cells, human heart tissue, Jurkat cells, mouse brain tissue, mouse heart tissue, mouse kidney tissue

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human pancreas cancer tissue, human colon tissue, human pancreas tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:5000
IP : 0.5-4.0 ug for IP and 1:500-1:5000 for WB
IHC : 1:50-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
voltage-dependent anion channel 1

Calculated molecular weight:
31 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
VDAC1

Synonyms
hVDAC1, Plasmalemmal porin, Porin, PORIN 31 HL, Porin 31HL, Porin 31HM, VDAC, VDAC 1, VDAC1
Background

VDAC1, also named as VDAC, Porin 31HM, Porin 31HL and Plasmalemmal porin, belongs to the eukaryotic mitochondrial porin family. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, to form a channel through the mitochondrial outer membrane and also the plasma membrane. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion. It is a 31kd membrane protein conserved in chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish.


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