CoraLite®594-conjugated Cardiac Troponin I Monoclonal antibody
Cardiac Troponin I Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat
Applications
IF/ICC
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1D5D6
验证数据展示
经过测试的应用
| Positive IF detected in | mouse heart tissue |
For other applications, we recommend the unconjugated version of this antibody, 66376-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
CL594-66376 targets Cardiac Troponin I in IF applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | IF/ICC |
| Cited Applications | IF |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Immunogen | Cardiac Troponin I fusion protein Ag16758 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | troponin I type 3 (cardiac) |
| Synonyms | Cardiac troponin I, CMD2A, CMH7, cTnI, RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle |
| Calculated Molecular Weight | 210 aa, 24 kDa |
| Observed Molecular Weight | 26-28 kDa |
| GenBank Accession Number | BC096165 |
| Gene Symbol | TNNI3 |
| Gene ID (NCBI) | 7137 |
| RRID | AB_2883572 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P19429 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Troponin I (TnI) is the inhibitory subunit of troponin, the structural protein involved in the regulation of striated muscle contraction. Cardiac Troponin I (cTnI) is produced by cardiac muscle. Two other TnI isoforms (slow sTnI and fast sTnI) are produced by slow-twitch and fast-twitch skeletal muscles, respectively. cTnI has been considered as one of the most specific and sensitive markers of myocardial damage like acute myocardial infarction (AMI) for decades. Detection of cTnI in serum is widely accepted as a diagnostic tool in acute coronary syndromes. This antibody is specific to cTnI, but not cross-react with skeletal TnI.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 Cardiac Troponin I antibody CL594-66376 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
FASEB Bioadv Progranulin deficiency exacerbates cardiac remodeling after myocardial infarction |