CoraLite® Plus 647 Anti-Mouse CD31 (390)

CD31 Monoclonal Antibody for IF/ICC, FC
Cat No. CL647-65058

产品说明书

CloneNo. 390

宿主/亚型

Rat / IgG2a, kappa

种属反应性

mouse

应用

IF/ICC, FC and More (1)

PECAM-1, Pecam1, PECAM 1, Pecam, 390

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inbEnd.3 cells
Positive FC detected inC57BL/6 mouse bone marrow cells
For other applications, we recommend the unconjugated version of this antibody, 65058-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 1 publications below

产品信息

CL647-65058 targets CD31 in IF/ICC, FC applications and shows reactivity with mouse samples.

经测试应用 IF/ICC, FC Application Description
文献引用应用IF
经测试反应性 mouse
免疫原 C3H/HeJ mouse hematopoietic progenitor cell line 32D 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 platelet/endothelial cell adhesion molecule 1
别名 PECAM-1, Pecam1, PECAM 1, Pecam, 390
GenBank蛋白编号BC008519
基因名称 CD31
Gene ID (NCBI) 18613
RRIDAB_2883659
偶联类型 CoraLite® Plus 647 Fluorescent Dye
最大激发/发射波长654 nm / 674 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDQ08481
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

实验方案

Product Specific Protocols
IF protocol for CL Plus 647 CD31 antibody CL647-65058Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
IF

iScience

SGMS1 facilitates osteogenic differentiation of MSCs and strengthens osteogenesis-angiogenesis coupling by modulating Cer/PP2A/Akt pathway

Authors - Kai Yang
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