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验证数据展示

  • FC experiment of human peripheral blood platelets using FITC-65185

    FC experiment of human peripheral blood platelets using FITC-65185

    1X10^6 human peripheral blood platelets were surface stained with 4.00 ul/test FITC Anti-Human CD61 (FITC-65185, Clone:VIPL2) (red) or isotype control antibody (blue). Cells were not fixed.

FITC Anti-Human CD61 (VIPL2)

CD61 Monoclonal Antibody for FC
Cat No. FITC-65185

产品说明书

CloneNo. VIPL2

宿主/亚型

Mouse / IgG1, kappa

种属反应性

Human, Non-human primates

应用

FC

别名

CD61, GP3A, GPIIIa, Integrin beta 3, ITGB3

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  FITC
规格: 
25tests
100tests

¥1960/ 100tests

浓度: 4 μl/test

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经过测试的应用

Positive FC detected inhuman peripheral blood platelets
Planning an IHC experiment? We recommend our IHCeasy ITGB3/CD61 Ready-To-Use IHC Kit. ITGB3/CD61 primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 4 μl per 10^6 cells in a 100 µl suspension or 4 μl per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65185 targets CD61 in FC applications and shows reactivity with Human, Non-human primates samples.

经测试应用 FC Application Description
经测试反应性 Human, Non-human primates
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
别名 CD61, GP3A, GPIIIa, Integrin beta 3, ITGB3
计算分子量 788 aa, 87 kDa
GenBank蛋白编号BC127666
基因名称 Integrin beta 3
Gene ID (NCBI) 3690
RRIDAB_2883819
偶联类型 FITC Fluorescent Dye
最大激发/发射波长494 nm / 520 nm
形式 Liquid
纯化方式The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
UNIPROT IDP05106
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

CD61 is a 110-kDa membrane glycoprotein that is also termed integrin β3 chain or GPIIIa. CD61 can associate with integrin αV chain (CD51) or integrin αIIb chain (CD41, GPIIb) to form heterodimeric receptors for cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, plasminogen, prothrombin, thrombospondin, vitronectin and von Willebrand factor (PMID: 7694604; 9251239; 2018971; 20628538). Integrin αVβ3 (CD51-CD61) is present on endothelium, smooth muscle, osteoclasts, platelets, some fibroblasts, some activated leukocytes and tumor cells (PMID: 7694604). GPllb-llla (CD41-CD61) is restricted in distribution to platelets and cells of megakaryoblastic potential and is required for platelet aggregation (PMID: 2018971; 16322781).

实验方案

Product Specific Protocols
FC protocol for FITC CD61 antibody FITC-65185Download protocol
Standard Protocols
Click here to view our Standard Protocols