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CID antibody (mAb) (Clone 4F8)

Host / Isotype

Rat / IgG2a

Reactivity

Drosophila

Applications

ICC, IF

CloneNo.

4F8

Cat No : 61735,61736 61735

Synonyms

CenH3, cid, BcDNA:RE21270, cenH3, CenH3/CID, CenH3[Cid], CenH3[CID], Cenp-A, CENP-A, CENP-A/Cid, CENP-A/CID, CENP-C, cenpA, CenpA, CENPA, CenpA/CID, CG13329, Cid, CID/CENP-A, Cid[Mel], Dmel\CG13329, drosophila, antibody, antibodies, monoclonal, mab, immunocytochemistry, icc, immunofluorescence, if, sample

验证数据展示

产品信息

Tested Applications ICC, IF

Tested Reactivity Drosophila
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Immunogen This antibody was raised against a recombinant protein corresponding to the N-terminus of drosophila CID.
Full Name CID antibody (mAb) (Clone 4F8)
Synonyms CenH3, cid, BcDNA:RE21270, cenH3, CenH3/CID, CenH3[Cid], CenH3[CID], Cenp-A, CENP-A, CENP-A/Cid, CENP-A/CID, CENP-C, cenpA, CenpA, CENPA, CenpA/CID, CG13329, Cid, CID/CENP-A, Cid[Mel], Dmel\CG13329, drosophila, antibody, antibodies, monoclonal, mab, immunocytochemistry, icc, immunofluorescence, if, sample
Molecular weight 35 kDa
GenBank accession numberNP_523730
RRIDAB_2793749
Purification Method Protein G Chromatography
Buffer Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

背景介绍

CID (Centromer Identifier) is the Drosophila histone H3 variant which replaces canonical H3 in centromeric chromatin at the inner plate of the kinetochore (similar to mammalian CENP-A). CID is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. It may serve as an epigenetic mark that propagates centromere identity through DNA replication and cell division.