细胞因子&活性蛋白
人源细胞(HEK293)表达的细胞因子&活性蛋白具有高生物活性、高稳定性、批次间的高度一致性，更接近天然人源蛋白的构象和翻译后修饰。
我们的人源表达系统确保蛋白质具有天然构象和翻译后修饰，以优化生物活性。无标签，没有异源成分。
不含动物成分
超低内毒素
无异源成分
无标签
无载体
HumanKine®重组蛋白是在HEK293细胞中产生的，无动物成分
细菌表达的蛋白质不具有翻译后修饰，例如磷酸化或糖基化。就活性而言，许多蛋白质需要糖基化和加工，这只能在真核系统中实现；特别是人源细胞表达系统，可以获得真正的人类蛋白质。
所有Humankine®重组蛋白均在Proteintech的cGMP级实验室生产，遵守严格的质量控制规定。
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真正的人源蛋白质
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天然构象与翻译后修饰
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高生物活性和稳定性
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从研究到cGMP的无缝过渡
为了促进从临床前到临床的平稳过渡，Humankine®提供了一系列仅用于研究（RUO）和cGMP级重组蛋白质，这些蛋白质从HEK293人类细胞中表达和纯化。RUO和cGMP产品均生产于cGMP标准车间，使用相同的表达系统、生产流程和操作程序，保证了这些产品质量和性能的一致性。
我们的cGMP产品与RUO的关键区别在于，我们坚持严格的质量流程，通过ISO13485认证并符合cGMP标准。cGMP级产品附带大量文件、全面的质量检监测和可追溯性。RUO等级提供可靠的产品，在早期研发期间更具成本效益。
cGMP制造工艺
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Resources
Time-Saving Dendritic Cell Generation No Medium Change - Less Reagents With HumanKine® GM-CSF and HumanKine IL4
HumanKine® IL-23 100x More Potent For Induction of Human Th17 Cells
Effective Polarization of Human Th17 Cells with Biologically Relevant HumanKine® TGFβ1, TGFβ2, and TGFβ3 Expressed in Human Cells
Efficient Induction of Th17 Cells with HumanKine® TGFβ1
Native Glycosylation Is Important For Biological Function and Activity of Recombinant Human Proteins
HumanKine® IL-17 Effective Tool for Autoimmune Disease Research
Effective Differentiation of Th17 Cells With HumanKine® Cytokines Expressed in Human Cells
HumanKine® Noggin Human Cell-expressed Glycosylated Disulfide-linked Homodimer
Mesenchymal Stem Cell
Wnt Signaling
Induced Pluripotent Stem Cell
TGF-beta Signaling
Haematopoietic Stem Cell
IL-6
BMP-2
Independent research demonstrates HEK293 derived BMP-2 is more active and stable than either E.coli or CHO derived BMP-2.
IL-2
Proteintech's HumanKine recombinant IL-2 is 40x more active than leading competitor product.
Read More
Wnt3A
High purity, high activity Wnt3A, without the high price.
Read More
Product Flyer
HumanKine Cytokines and Growth Factors.
Read More
Product Flyer
cGMP Grade HumanKine Cytokines and Growth Factors.
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Recent Publications
Front. Bioeng. Biotechnol.
Mechano-Hypoxia Conditioning of Engineered Human Meniscus
Alexander R A Szojka
Br J Pharmacol
Yanhong Pan
Int Immunopharmacol
Siqi Shao
Proc Natl Acad Sci U S A
Takahiro Nishio
Nat Commun
Extracellular mRNA transported to the nucleus exerts translation-independent function
Takeshi Tomita
Articles
ISO 13485 certification - cGMP compliant proteins
Proteintech announces ISO 13485 Certification for its HumanKine® Human Cell-expressed Cytokines and Growth Factors.
Top 4 considerations when choosing your recombinant proteins
Due to the importance in cell culture and therapeutic systems, there are several considerations to evaluate when choosing a recombinant protein for your own cultures.
What do you get when you buy a cGMP-Grade product?
cGMP manufacturing, benefits, and ISO certifications explained.
6 reasons why HEK293 proteins are superior for clinical applications
Find out the benefits of HumanKine® recombinant proteins, cytokines and growth factors.
ISO 13485 certification - cGMP compliant proteins
Proteintech announces ISO 13485 Certification for its HumanKine® Human Cell-expressed Cytokines and Growth Factors.
Top 4 considerations when choosing your recombinant proteins
Due to the importance in cell culture and therapeutic systems, there are several considerations to evaluate when choosing a recombinant protein for your own cultures.
What do you get when you buy a cGMP-Grade product?
cGMP manufacturing, benefits, and ISO certifications explained.
6 reasons why HEK293 proteins are superior for clinical applications
Find out the benefits of HumanKine® recombinant proteins, cytokines and growth factors.
New cGMP Laboratory
Proteintech announces completion of its new cGMP laboratory.
FGF Basic TS
Thermostable FGF does not require media changes over the weekend.