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Ddit3 antibody (mAb) (Clone 9C8)

Host / Isotype

Mouse / IgG2b

Reactivity

Mouse

Applications

IP, WB

CloneNo.

9C8

Cat No : 61349,61350 61349

Synonyms

Ddit3, DNA-damage-inducible transcript 3, DDIT-3, CHOP10, CEBPZ, GADD153, C/EBP zeta, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, DNA damage-inducible transcript 3 protein, Growth arrest and DNA damage-inducible protein GADD153, C/EBP-homologous protein, CHOP-10, antibody, monoclonal, mAb, sample

验证数据展示

产品信息

Tested Applications IP, WB

Tested Reactivity Mouse
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen This antibody was raised against full-length recombinant mouse Ddit3 protein.
Full Name Ddit3 antibody (mAb) (Clone 9C8)
Synonyms Ddit3, DNA-damage-inducible transcript 3, DDIT-3, CHOP10, CEBPZ, GADD153, C/EBP zeta, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, DNA damage-inducible transcript 3 protein, Growth arrest and DNA damage-inducible protein GADD153, C/EBP-homologous protein, CHOP-10, antibody, monoclonal, mAb, sample
Molecular weight 29 kDa
GenBank accession numberNP_031863
RRIDAB_2614958
Purification Method Protein G Chromatography
Buffer Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

背景介绍

Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.