• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

PIM2 antibody (mAb) (Clone CHU61)

Host / Isotype

Rat / IgG2a

Reactivity

Human

Applications

IHC, WB

CloneNo.

CHU61

Cat No : 61159,61160 61159

Synonyms

PIM2, serine threonine protein kinase, CAMK, pim-2, pim2h, pim-2h, pim 2, I-kB kinase, NF-kB, BAD, lymphocytes, leukemia, lymphoma, adenocarcinomas, hepatocellular carcinomas, monoclonal, clone CHU61, sample

验证数据展示

  • PIM2 antibody (mAb) tested by Immunohistochemistry PIM2 detected by immunohistochemistry in paraffin-embedded human tonsil cells.

    PIM2 antibody (mAb) tested by Immunohistochemistry PIM2 detected by immunohistochemistry in paraffin-embedded human tonsil cells.

  • PIM2 antibody (mAb) tested by Western blot Ramos cell extract (100 ug per lane) probed with PIM2 antibody (mAb).

    PIM2 antibody (mAb) tested by Western blot Ramos cell extract (100 ug per lane) probed with PIM2 antibody (mAb).

产品信息

Tested Applications IHC, WB

Applications Validated by Active Motif: IHC: 2 ug/ml dilution WB: 0.5 - 2 ug/ml dilution The antibody is suitable for IHC on paraffin sections. Frozen sections are not recommended. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91239.
Tested Reactivity Human
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Immunogen This PIM2 antibody was raised against a recombinant protein corresponding to human PIM2.
Full Name PIM2 antibody (mAb) (Clone CHU61)
Synonyms PIM2, serine threonine protein kinase, CAMK, pim-2, pim2h, pim-2h, pim 2, I-kB kinase, NF-kB, BAD, lymphocytes, leukemia, lymphoma, adenocarcinomas, hepatocellular carcinomas, monoclonal, clone CHU61, sample
Molecular weight 37 kDa
GenBank accession numberNP_006866
RRIDAB_2615012
Purification Method Protein G Chromatography
Buffer Purified rat IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

背景介绍

PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-kB kinase/NF-kB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas.