• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

SMARCAL1 / HARP antibody (mAb) (Clone 4B10)

Host / Isotype

Mouse / IgG1

Reactivity

Bovine, Human, Mouse

Applications

IP, WB

CloneNo.

4B10

Cat No : 61115,61116 61115

Synonyms

SMARCAL1, HARP, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, DNA-dependent ATPase A, SWI / SNF, ATP-dependent annealing helicase activity, DNA replication forks, Replication Protein A, RPA, Schimke immuno-osseous dysplasia, SIOD, SIOD causes spondyloepiphyseal dysplasia, bone growth, short stature, skeletal abnormalities, problems with vision and hearing, renal dysfunction and T-cell immunodeficiency, sample, polyclonal

验证数据展示

产品信息

Tested Applications IP, WB

Tested Reactivity Bovine, Human, Mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen This SMARCAL1 / HARP antibody was raised against purifed bovine SMARCAL1 / HARP protein.
Full Name SMARCAL1 / HARP antibody (mAb) (Clone 4B10)
Synonyms SMARCAL1, HARP, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, DNA-dependent ATPase A, SWI / SNF, ATP-dependent annealing helicase activity, DNA replication forks, Replication Protein A, RPA, Schimke immuno-osseous dysplasia, SIOD, SIOD causes spondyloepiphyseal dysplasia, bone growth, short stature, skeletal abnormalities, problems with vision and hearing, renal dysfunction and T-cell immunodeficiency, sample, polyclonal
Molecular weight 150 kDa
GenBank accession numberNP_788839
RRIDAB_2614999
Purification Method Protein G Chromatography
Buffer Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

背景介绍

SMARCAL1 / HARP (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, DNA-dependent ATPase A) is a member of the SWI / SNF family of ATPases and chromatin remodeling proteins. Unlike other SWI / SNF family members, SMARCAL1 / HARP has not been shown to remodel chromatin, but possesses an ATP-dependent annealing helicase activity. SMARCAL1 reanneals single-stranded DNA bubbles in DNA at DNA replication forks that are bound by Replication Protein A (RPA). Defects in SMARCAL1 / HARP are a cause of Schimke immuno-osseous dysplasia (SIOD) SIOD causes spondyloepiphyseal dysplasia (a disorder of bone growth that results in short stature, skeletal abnormalities, and problems with vision and hearing), renal dysfunction and T-cell immunodeficiency.