AKNA Polyclonal antibody

AKNA Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 23785-1-AP

Print datasheet

Synonyms

AKNA, AT hook transcription factor, KIAA1968, Microtubule organization protein AKNA, RP11 82I1.4



经过测试的应用

Positive WB detected inK-562 cells
Planning an IHC experiment? We recommend our IHCeasy AKNA Ready-To-Use IHC Kit. AKNA primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

The immunogen of 23785-1-AP is AKNA Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human
Cited Reactivityhuman
Immunogen AKNA fusion protein Ag20662 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name AT-hook transcription factor
Synonyms AKNA, AT hook transcription factor, KIAA1968, Microtubule organization protein AKNA, RP11 82I1.4
Calculated Molecular Weight 155 kDa
Observed Molecular Weight 65-70 kDa
GenBank Accession NumberBC055285
Gene Symbol AKNA
Gene ID (NCBI) 80709
RRIDAB_2879324
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ7Z591
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)

实验方案

Product Specific Protocols
WB protocol for AKNA antibody 23785-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Biomed Res Int

AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways.

Authors - Gang Wang