CCL17 Polyclonal antibody

CCL17 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 22342-1-AP

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Synonyms

A 152E5.3, ABCD 2, C C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small inducible cytokine A17, TARC



经过测试的应用

Positive IHC detected inhuman colon tissue, human placenta tissue, human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 2 publications below

产品信息

The immunogen of 22342-1-AP is CCL17 Fusion Protein expressed in E. coli.

Tested Applications IHC, ELISA Application Description
Cited ApplicationsIHC
Tested Reactivity human
Cited Reactivityhuman
Immunogen CCL17 fusion protein Ag17832 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chemokine (C-C motif) ligand 17
Synonyms A 152E5.3, ABCD 2, C C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small inducible cytokine A17, TARC
Calculated Molecular Weight 94 aa, 11 kDa
GenBank Accession NumberBC112066
Gene Symbol CCL17
Gene ID (NCBI) 6361
RRIDAB_2879081
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ92583
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CCL17, also named as TARC, is a member of the CC chemokine family, and is highly expressed by thymus and other cells, including keratinocytes, endothelial cells, dendritic cells, bronchial epithelial cells and fibroblasts. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 induced chemotaxis and Ca2+ influx in the cells stably expressing CCR4, thereby demonstrating the ligand-receptor relationship between CCL17 and CCR4.

实验方案

Product Specific Protocols
IHC protocol for CCL17 antibody 22342-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Br J Haematol

Expression of multiple cytokines and chemokine receptor 4 in angioimmunoblastic T-cell lymphoma with abundant plasma cell infiltration involving the skin.

Authors - Shoko Nakayama
humanIHC

Hemasphere

NOTCH1 fusions in pediatric T-cell lymphoblastic lymphoma: A high-risk subgroup with CCL17 (TARC) levels as diagnostic biomarker

Authors - Emma Kroeze