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  • KD/KO Validated

GIMAP7 Polyclonal antibody

GIMAP7 Polyclonal Antibody for WB, IF/ICC, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

WB, IF/ICC, IP, ELISA and More (1)

Conjugate

Unconjugated

Cat no : 17293-1-AP

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Synonyms

Immunity-associated nucleotide 7 protein, IAN-7, IAN7, GTPase IMAP family member 7



经过测试的应用

Positive WB detected inJurkat cells
Positive IP detected inJurkat cells
Positive IF/ICC detected inHepG2 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICCIF/ICC : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17293-1-AP targets GIMAP7 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, IP, ELISA Application Description
Cited ApplicationsWB, IHC
Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Immunogen GIMAP7 fusion protein Ag11171 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name GTPase, IMAP family member 7
Synonyms Immunity-associated nucleotide 7 protein, IAN-7, IAN7, GTPase IMAP family member 7
Calculated Molecular Weight 300 aa, 35 kDa
Observed Molecular Weight 34 kDa
GenBank Accession NumberBC027613
Gene Symbol GIMAP7
Gene ID (NCBI) 168537
RRIDAB_2111885
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NHV1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GIMAP7, also known as hIAN7 or IAN 7, is a transmembrane protein located in the endoplasmic reticulum and Golgi apparatus. GIMAP7 can promote oxidative stress and apoptosis in ovarian granulosa cells in Polycystic ovary syndrome by inhibiting the SHH signalling pathway(PMID: 36581994). The MW of this protein is 34 kDa, and this antibody specially recognises the 34 kDa protein.

实验方案

Product Specific Protocols
WB protocol for GIMAP7 antibody 17293-1-APDownload protocol
IF protocol for GIMAP7 antibody 17293-1-APDownload protocol
IP protocol for GIMAP7 antibody 17293-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Front Oncol

Transcriptome-Based Network Analysis Unveils Eight Immune-Related Genes as Molecular Signatures in the Immunomodulatory Subtype of Triple-Negative Breast Cancer.

Authors - Jinguo Zhang
human,ratWB,IHC

J Ovarian Res

GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway

Authors - Anran Xu
  • KD Validated
human,mouseWB,IHC

Thorac Cancer

GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway

Authors - Liyuan Cui
  • KD Validated