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  • KD/KO Validated

TRIM44 Polyclonal antibody

TRIM44 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 11511-1-AP

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Synonyms

DIPB, HSA249128, MC7, Protein DIPB, TRIM44, tripartite motif containing 44



经过测试的应用

Positive WB detected inmouse testis tissue, human liver tissue
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11511-1-AP targets TRIM44 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB, IHC, IF, IP
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen TRIM44 fusion protein Ag2070 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tripartite motif-containing 44
Synonyms DIPB, HSA249128, MC7, Protein DIPB, TRIM44, tripartite motif containing 44
Calculated Molecular Weight 344 aa, 38 kDa
Observed Molecular Weight 50-55 kDa
GenBank Accession NumberBC024031
Gene Symbol TRIM44
Gene ID (NCBI) 54765
RRIDAB_2303802
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96DX7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TRIM44 is one of the family member of TRIM protein, which contains an N-terminal ubiquitin hydrolase-type zinc-finger domain, followed by a coiled-coil domain, a zinc-finger B-box homology domain, and a second coiled-coil domain near the C-terminus. Members of the TRIM protein family are involved in various cellular processes, such as cell proliferation, oncogenesis and antiviral defense. This is a rabbit polyantibody raised against full length of human TRIM44.

实验方案

Product Specific Protocols
WB protocol for TRIM44 antibody 11511-1-APDownload protocol
IHC protocol for TRIM44 antibody 11511-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Gastroenterology

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.

Authors - Peters Christopher J CJ
humanWB,IF

Autophagy

TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins.

Authors - Lin Lyu
  • KO Validated
humanIP,WB,IF

Oncogene

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

Authors - Lin Lyu
  • KO Validated
humanWB

J Immunol

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.

Authors - Yang Bo B
ratWB,IHC,IF

Dis Model Mech

Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.

Authors - Xiao-Yu Jiang
humanWB,IHC

Cancer Sci

TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.

Authors - Dian Xiong