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验证数据展示

  • WB analysis of PC-3 using 12028-1-AP

    WB analysis of PC-3 using 12028-1-AP

    PC-3 cells were subjected to SDS PAGE followed by western blot with 12028-1-AP (Cadherin-11 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Cadherin-11 Polyclonal antibody

Cadherin-11 Polyclonal Antibody for WB, ELISA
Cat No. 12028-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

CDH11, CAD11, Cadherin 11, CDHOB, OB

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inPC-3 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12028-1-AP targets Cadherin-11 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 Cadherin-11 fusion protein Ag2659 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cadherin 11, type 2, OB-cadherin (osteoblast)
别名 CDH11, CAD11, Cadherin 11, CDHOB, OB
计算分子量 796 aa, 88 kDa
观测分子量120 kDa
GenBank蛋白编号BC013609
基因名称 CDH11
Gene ID (NCBI) 1009
RRIDAB_3085386
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP55287
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-11 (CDH11), also known osteoblast cadherin (OB-cadherin) or OSF-4, was identified initially in a mouse osteoblastic cell line and human osteosarcoma (PMID: 8163513). Cadherin-11 is a single pass transmembrane protein consisting of an extracellular domain which contains five repeat sequences (EC1-EC5), a transmembrane segment and a cytoplasmic domain which links catenins to the actin and microtubule cytoskeleton (PMID: 8163513; 33442417). It has been shown that cadherin-11 plays important roles in the occurrence and development of a lot of diseases, arthritis, cancer, aortic calcification disease, dermatosis (PMID: 33442417).

实验方案

Product Specific Protocols
WB protocol for Cadherin-11 antibody 12028-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols