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DPYD Polyclonal antibody

DPYD Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 25690-1-AP

Print datasheet

Synonyms

DHP, DHPDHASE, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPD, DPYD

验证数据展示

  • WB analysis of mouse liver using 25690-1-AP

    WB analysis of mouse liver using 25690-1-AP

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 25690-1-AP (DPYD antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse liver tissue
Planning an IHC experiment? We recommend our IHCeasy DPYD Ready-To-Use IHC Kit. DPYD primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

25690-1-AP targets DPYD in WB, ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity mouse
Immunogen DPYD fusion protein Ag20885 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dihydropyrimidine dehydrogenase
Synonyms DHP, DHPDHASE, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPD, DPYD
Calculated Molecular Weight 1025 aa, 111 kDa
Observed Molecular Weight111 kDa
GenBank Accession NumberBC008379
Gene Symbol DPYD
Gene ID (NCBI) 1806
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ12882
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

实验方案

Product Specific Protocols
WB protocol for DPYD antibody 25690-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols