MSH6 Monoclonal antibody

MSH6 Monoclonal Antibody for IHC, ELISA
Cat No. 66172-2-Ig
CloneNo. 5B5A7

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, ELISA

hMSH6, GTMBP, GTBP, G/T mismatch-binding protein, G/T mismatch binding protein

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size: 

-/ -


经过测试的应用

Positive IHC detected inhuman colon cancer tissue, human colon tissue, human tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy MSH6 Ready-To-Use IHC Kit. MSH6 primary antibody included.

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66172-2-Ig targets MSH6 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen MSH6 fusion protein Ag12645 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name mutS homolog 6 (E. coli)
Synonyms hMSH6, GTMBP, GTBP, G/T mismatch-binding protein, G/T mismatch binding protein
Calculated Molecular Weight 153 kDa
Observed Molecular Weight150-160 kDa
GenBank Accession NumberBC004246
Gene Symbol MSH6
Gene ID (NCBI) 2956
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP52701
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MSH6, also named as DNA mismatch repair protein Msh6 or GTMBP, is a 1360 amino acid protein, which contains one PWWP domain and belongs to the DNA mismatch repair MutS family. MSH6 localizes in the nucleus and is a component of the post-replicative DNA mismatch repair system. Msh2 and Msh6 form a protein complex required to repair mismatches generated during DNA replication.

实验方案

Product Specific Protocols
IHC protocol for MSH6 antibody 66172-2-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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