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IL-4RA Monoclonal antibody, PBS Only (Capture/Detector)

IL-4RA Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgM

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3F12E8

Cat no : 67051-3-PBS

Print datasheet

Synonyms

IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein

验证数据展示

  • Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-2-PBS. Standard:Ag28411. Range: 1.563-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-4-PBS. Detection antibody: 67051-3-PBS. Standard:Ag28411. Range: 0.781-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3, IL4R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-5-PBS. Standard:Ag28411. Range: 0.195-100 ng/mL.

产品信息

67051-3-PBS targets IL-4RA as part of a matched antibody pair:

MP50242-1: 67051-3-PBS capture and 67051-2-PBS detection (validated in Cytometric bead array)

MP50242-2: 67051-4-PBS capture and 67051-3-PBS detection (validated in Cytometric bead array)

MP50242-3: 67051-3-PBS capture and 67051-5-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen IL-4RA fusion protein Ag28411 种属同源性预测
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Full Name interleukin 4 receptor
Synonyms IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein
Calculated Molecular Weight 90 kDa
GenBank Accession NumberNM_000418
Gene Symbol IL-4R
Gene ID (NCBI) 3566
Conjugate Unconjugated
Form Liquid
Purification MethodEuglobulin precipitation
UNIPROT IDP24394
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.