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MORC3 Monoclonal antibody

MORC3 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1E1E1

Cat no : 68370-1-Ig

Print datasheet

Synonyms

KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3

验证数据展示

  • WB analysis using 68370-1-Ig

    WB analysis using 68370-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 68370-1-Ig (MORC3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control.

  • WB analysis using 68370-1-Ig

    WB analysis using 68370-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 68370-1-Ig (MORC3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control.

经过测试的应用

Positive WB detected inLNCaP cells, NIH/3T3 cells, HeLa cells, HepG2 cells, HEK-293 cells, Jurkat cells, K-562 cells, 4T1 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

68370-1-Ig targets MORC3 in WB, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, mouse
Immunogen MORC3 fusion protein Ag21867 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name MORC family CW-type zinc finger 3
Synonyms KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3
Calculated Molecular Weight 939 aa, 107 kDa
Observed Molecular Weight130 kDa
GenBank Accession NumberBC132731
Gene Symbol MORC3
Gene ID (NCBI) 23515
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ14149
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MORC3, also named as MORC family CW-type zinc finger protein 3 or NXP2, is a 939 amino acid protein, which contains 1 CW-type zinc finger. MORC3 localizes in the nucleus and are expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. MORC3 as Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs and recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. It may be required for influenza A transcription during viral infection. The calculated molecular weight of MORC3 is a 107 kDa, but the Sumoylated MORC3 protein is about 130 kDa.

实验方案

Product Specific Protocols
WB protocol for MORC3 antibody 68370-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols