验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, A431 cells, LNCaP cells, HeLa cells, TF-1 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68530-1-Ig targets MORC2 in WB, ELISA applications and shows reactivity with Human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | Human |
| 免疫原 | MORC2 fusion protein Ag19605 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | MORC family CW-type zinc finger 2 |
| 别名 | KIAA0852, MORC2, ZCW3, ZCWCC1 |
| 计算分子量 | 970 aa, 111 kDa |
| 观测分子量 | 118 kDa |
| GenBank蛋白编号 | BC136782 |
| 基因名称 | MORC2 |
| Gene ID (NCBI) | 22880 |
| RRID | AB_3085238 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q9Y6X9 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. It can be recruited by HUSH to target site in heterochromatin. MORC2 also recruits histone deacetylases, such as HDAC4, to promoter regions, causing local histone H3 deacetylation and transcriptional repression of genes.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for MORC2 antibody 68530-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |