PRODH Monoclonal antibody
PRODH Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, rabbit, pig
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2C3G5
验证数据展示
经过测试的应用
| Positive WB detected in | mouse liver tissue, pig brain tissue, rabbit brain tissue, rat brain tissue, mouse brain tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68621-1-Ig targets PRODH in WB, ELISA applications and shows reactivity with Human, mouse, rat, rabbit, pig samples.
| Tested Applications | WB, ELISA Application Description |
| Tested Reactivity | Human, mouse, rat, rabbit, pig |
| Immunogen | PRODH fusion protein Ag18429 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | proline dehydrogenase (oxidase) 1 |
| Synonyms | FLJ33744, HSPOX2, p53 induced gene 6 protein, PIG6, POX, POX2, PRODH, PRODH1, PRODH2, Proline oxidase, Proline oxidase 2, SCZD4, TP53I6 |
| Calculated Molecular Weight | 600 aa, 68 kDa |
| Observed Molecular Weight | 56 kDa, 66 kDa |
| GenBank Accession Number | BC118597 |
| Gene Symbol | PRODH |
| Gene ID (NCBI) | 5625 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | O43272 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PRODH(Proline dehydrogenase 1, mitochondrial) is also named as PIG6, HSPOX2, PRODH1, PRODH2, POX, SCZD4, TP53I6 and belongs to the proline oxidase family. It is an oxidoreductase involved in the transfer of redox potential across the mitochondrial membrane and catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). High PRODH activity is sufficient to induce mitochondria-mediated apoptosis in the presence of proline. Defects in PRODH are the cause of hyperprolinemia type 1 (HP-1) and defects in PRODH are associated with susceptibility to schizophrenia type 4 (SCZD4). This protein has 3 isoforms produced by alternative splicing with the molecular mass of 68 kDa, 59 kDa and 56 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PRODH antibody 68621-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |