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LAMR1/RPSA Recombinant antibody, PBS Only (Detector)

LAMR1/RPSA Uni-rAbTM Recombinant Antibody for Sandwich ELISA, Indirect ELISA, Sample test

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Sandwich ELISA, Indirect ELISA, Sample test

Conjugate

Unconjugated

CloneNo.

240461B1

Cat no : 83495-6-PBS

Print datasheet

Synonyms

LAMR1,RPSA, RPSA, 67LR, 67 kDa laminin receptor, 40S ribosomal protein SA

验证数据展示

  • Sandwich ELISA standard curve of MP00494-4

    Sandwich ELISA standard curve of MP00494-4

    Sandwich ELISA standard curve of MP00494-4, Human LAMR1/RPSA Recombinant Matched Antibody Pair - PBS only. 83495-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag6033. 83495-6-PBS was HRP conjugated as the detection antibody. Range: 1.56-100 ng/mL.

  • Sample test of MP00494-4

    Sample test of MP00494-4

    The mean LAMR1/RPSA concentration was determined to be 387.00 ng/mL in COLO 320 cell extract based on a 2.00 mg/mL extract load, 218.85 ng/mL in HeLa cell extract based on a 1.20 mg/mL extract load and 291.26 ng/mL in HEK-293 cell extract based on a 1.20 mg/mL extract load.

产品信息

83495-6-PBS targets LAMR1/RPSA as part of a matched antibody pair:

MP00494-4: 83495-1-PBS capture and 83495-6-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Sandwich ELISA, Indirect ELISA, Sample test Application Description
Tested Reactivity human
Immunogen LAMR1/RPSA fusion protein Ag6033 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name ribosomal protein SA
Synonyms LAMR1,RPSA, RPSA, 67LR, 67 kDa laminin receptor, 40S ribosomal protein SA
Calculated Molecular Weight 33 kDa
GenBank Accession NumberBC050688
Gene Symbol RPSA
Gene ID (NCBI) 3921
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP08865
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The ribosomal protein SA (RPSA), previously named 67 kD laminin receptor(67LR), 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein, is a multifunctional protein, that plays a role in a number of pathological processes, such as cancer and prion diseases. It is overexpressed in various cancer cell lines, and the the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. This antibody is a rabbit polyclonal antibody raised against full length RPSA of human origin. This antibody is specific to RPSA (LAMR1).67LR derives from homo- or hetero- dimerization of a 37 kDa cytosolic precursor (37LRP)], most probably by fatty acid acylation. 37LRP is mostly found in the cytosol and nucleus [10] where it is involved in translational processes and maintenance of nuclear structures, respectively. 67LR is localized at the cell surface and it not only serves as a receptor for LM but also acts as a receptor for elastin, carbohydrates and the cellular prion protein.