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TLR6 Recombinant antibody

TLR6 Uni-rAbTM Recombinant Antibody for IF-P, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IF-P, ELISA

Conjugate

Unconjugated

CloneNo.

241926F2

Cat no : 84811-2-RR

Print datasheet

Synonyms

Toll-like receptor 6, toll like receptor 6, CD286, 241926F2

验证数据展示

  • IF Staining of mouse spleen using 84811-2-RR

    IF Staining of mouse spleen using 84811-2-RR

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using TLR6 antibody (84811-2-RR, Clone: 241926F2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IF Staining of mouse spleen using 84811-2-RR

    IF Staining of mouse spleen using 84811-2-RR

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using TLR6 antibody (84811-2-RR, Clone: 241926F2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IF-P detected inmouse spleen tissue

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84811-2-RR targets TLR6 in IF-P, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IF-P, ELISA Application Description
Tested Reactivity human, mouse
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name toll-like receptor 6
Synonyms Toll-like receptor 6, toll like receptor 6, CD286, 241926F2
Calculated Molecular Weight 480 aa, 56 kDa
GenBank Accession NumberBC111755
Gene Symbol TLR6
Gene ID (NCBI) 10333
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9Y2C9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TLR6, also known as CD286, belongs to the Toll-like receptor (TLR) family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR6 can form a heterodimer with TLR2. TLR6 and TLR2 are both recruited to the macrophage phagosome, where they recognize peptidoglycan, a Gram-positive pathogen component (PMID: 11095740). TLR6 interacts with CD36, following CD36 stimulation by oxLDL or amyloid-beta 42, and forms a heterodimer with TLR4. The trimeric complex is internalized and triggers an inflammatory response.

实验方案

Product Specific Protocols
IF protocol for TLR6 antibody 84811-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols