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Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody

PDGFR alpha/CD140a Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241658H4

Cat no : 98141-1-RR

Print datasheet

Synonyms

PDGFRA, CD140a antigen, CD140A, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor

验证数据展示

  • FC experiment of MG-63 using 98141-1-RR

    FC experiment of MG-63 using 98141-1-RR

    1x10^6 MG-63 cells (left) or A-172 cells (right) were surface stained with 0.25 ug Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody (98141-1-RR, Clone: 241658H4) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98141-1-RR

    Affinity and Kinetic Characterization of 98141-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98141-1-RR against Human PDGFR alpha/CD140a were performed. The affinity constant is 2.26 nM.

经过测试的应用

Positive FC detected inMG-63 cells

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98141-1-RR targets PDGFR alpha/CD140a in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name platelet-derived growth factor receptor, alpha polypeptide
Synonyms PDGFRA, CD140a antigen, CD140A, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor
Calculated Molecular Weight 123 kDa
GenBank Accession NumberBC015186
Gene Symbol PDGFR alpha
Gene ID (NCBI) 5156
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP16234
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

实验方案

Product Specific Protocols
FC protocol for PDGFR alpha/CD140a antibody 98141-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols