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Recombinant Human Syndecan-1/CD138 protein (Myc Tag, His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

Myc Tag, His Tag

生物活性

未测试

Cat no : Eg0132

Print datasheet

Synonyms

CD138, SDC, SDC1, SYND1, syndecan

验证数据展示

  • Purity of Recombinant Human Syndecan-1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Syndecan-1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Syndecan-1 protein Gln23-Gly254 (Accession# AAH08765.1) with a Myc tag and a His tag at the C-terminus.
基因ID 6382
蛋白编号 AAH08765.1
预测分子量 28.9 kDa
SDS-PAGE 43-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD138, also known as Syndecan-1 (SDC1), is a member of the transmembrane heparan sulfate proteoglycan family. CD138 acts as an extracellular matrix receptor and participates in many cellular functions, including cell-cell adhesion and cell-matrix adhesion. CD138 is expressed on plasma cells and various epithelial cell types. Altered CD138 expression has been described in many different tumor types. CD138 can be shed form the cell surface and exist as a soluble form, which has paracrine and autocrine functions and functions as competitor of transmembrane CD138 for growth factors and other extracellular ligands.

参考文献:

1. M V Dhodapkar, et al. (1998) Blood.91(8):2679-2688.
2. Fionnuala P O'Connell, et al. (2004) Am J Clin Pathol. 121(2):254-263.
3. Robin E Gandley, et al. (2016) PLoS One. 11(6):e0157608.
4. Simon Kind, et al. (2019) Dis Markers. 2019:4928315.