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Recombinant Human CCL17/TARC protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0379

Print datasheet

Synonyms

CCL17, TARC, C C motif chemokine 17, CC chemokine TARC, C-C motif chemokine 17

验证数据展示

  • Purity of Recombinant Human CCL17 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CCL17 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human CCL17 protein Ala24-Ser94 (Accession# Q92583) with a His tag at the C-terminus.
基因ID 6361
蛋白编号 Q92583
预测分子量 11.9 kDa
SDS-PAGE 15-19 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL17, also named as TARC, is a member of the CC chemokine family, and is highly expressed by thymus and other cells, including keratinocytes, endothelial cells, dendritic cells, bronchial epithelial cells and fibroblasts. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 induced chemotaxis and Ca2+ influx in the cells stably expressing CCR4, thereby demonstrating the ligand-receptor relationship between CCL17 and CCR4.

参考文献:

1. Imai T. et al. (1996) J Biol Chem. 271:21514-1.
2. Sallusto F. et al. (1998) Eur J Immunol. 28:2760-9.
3. Campbell JJ. et al. (1999) Nature. 400:776-80.
4. Vestergaard C.et al. (1999) J Clin Invest. 104:1097-105.
5. Sekiya T.et al. (2000) J Immunol.165:2205-13.
6. Yu B.et al. (2000) J Dermatol Sci.30:29-36.