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Recombinant Human TMEM119 protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0796

Print datasheet

Synonyms

TMEM119, OBIF, Osteoblast induction factor, transmembrane protein 119, UNQ731/PRO1415

验证数据展示

  • Purity of Recombinant Human TMEM119 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human TMEM119 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human TMEM119 protein Thr118-Val283 (Accession# Q4V9L6) with a His tag at the C-terminus.
基因ID 338773
蛋白编号 Q4V9L6
预测分子量 18.1 kDa
SDS-PAGE 28-32 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

TMEM119, also known as Osteoblast Induction Factor (OBIF), plays important role in bone formation and normal bone mineralization. It is a highly expressed microglia-specific marker in both mouse and human. TMEM119 implicated in various cancers including gastric, osteosarcoma and hepatocellular carcinoma.

参考文献:

1.Zheng P. et al. (2018) Oncol Lett. 15(6):8281-8286. 
2.Jiang ZH. et al. (2017) Exp Mol Med. 49(5):e329. 
3.Bai KH. et al. (2020) Cancer Med. 9(12):4290-4298.