Recombinant Human FSTL3/FLRG protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0949

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Synonyms

FLRG, FSTL3, Follistatin like protein 3, follistatin-like 3, Follistatin-like protein 3



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human FSTL3 protein Met27-Val263 (Accession# O95633-1) with a His tag at the C-terminus.
基因ID 10272
蛋白编号 O95633-1
预测分子量 25.8 kDa
SDS-PAGE 30-36 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Follistatin-like 3 (FSTL3), also called follistatin-related protein or follistatin-related gene (FLRG) protein, is a highly conserved monomer secreted glycoprotein located on chromosome 19p13.3. The FSTL3 gene is the target of a novel chromosomal rearrangement discovered by Hayette et al in 1998 in B cells of patients with chronic lymphocytic leukemia. FSTL3 can modulate target gene expression via members of the transforming growth factor β (TGF-β) superfamily. Recent literatures have revealed that FSTL3 regulates multiple biological processes, including cell differentiation, aging, obesity development, arteriosclerosis development, and tumor progression.

参考文献:

1. S Hayette. et al. (1998) Oncogene. 16(22):2949-54. 2. Yisrael Sidis. et al. (2002) Endocrinology. 143(5):1613-24 3. Yisrael Sidis. Et al. (2005) Endocrinology. 146(1):130-6.