Recombinant Human FSTL3/FLRG protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human FSTL3 protein Met27-Val263 (Accession# O95633-1) with a His tag at the C-terminus. |
基因ID | 10272 |
蛋白编号 | O95633-1 |
预测分子量 | 25.8 kDa |
SDS-PAGE | 30-36 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Follistatin-like 3 (FSTL3), also called follistatin-related protein or follistatin-related gene (FLRG) protein, is a highly conserved monomer secreted glycoprotein located on chromosome 19p13.3. The FSTL3 gene is the target of a novel chromosomal rearrangement discovered by Hayette et al in 1998 in B cells of patients with chronic lymphocytic leukemia. FSTL3 can modulate target gene expression via members of the transforming growth factor β (TGF-β) superfamily. Recent literatures have revealed that FSTL3 regulates multiple biological processes, including cell differentiation, aging, obesity development, arteriosclerosis development, and tumor progression.
参考文献:
1. S Hayette. et al. (1998) Oncogene. 16(22):2949-54. 2. Yisrael Sidis. et al. (2002) Endocrinology. 143(5):1613-24 3. Yisrael Sidis. Et al. (2005) Endocrinology. 146(1):130-6.