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Recombinant Human Coagulation Factor III/Tissue Factor protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg1052

Print datasheet

Synonyms

CD142, Coagulation factor III, F3, Tissue factor, TF

验证数据展示

  • Purity of Recombinant Human Coagulation Factor III was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Coagulation Factor III was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Coagulation Factor III protein Ser33-Glu251 (Accession# P13726-1) with a His tag at the C-terminus.
基因ID 2152
蛋白编号 P13726-1
预测分子量 25.9 kDa
SDS-PAGE 32-40 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Tissue Factor (TF), also named CD142, coagulation factor III or F3, is the primary initiator of the blood coagulation cascade and plays an essential role in hemostasis.

参考文献:

1.Witkowski,M.et al.(2016) TRENDS CARDIOVAS MED.26(4):297-303.
2.Wu,R.et al.(2021) Front Immunol.12:641750.
3.Kinchen J.et al.(2018) Cell.175:372-386.e17. 
4.Unruh D.et al.(2020) J.Hematol.Oncol.13:93.