Recombinant Human CD44 protein (His Tag)
ED50
/
Species
Human
Purity
>90 %, SDS-PAGE
GeneID
960
Accession
P16070-1
验证数据展示
Technical Specifications
| Purity | >90 %, SDS-PAGE |
| Endotoxin Level | <1.0 EU/μg protein, LAL method |
| Biological Activity |
Not tested |
| Source | HEK293-derived Human CD44 protein Gln21-Glu649 (Accession# P16070-1) with a His tag at the C-terminus. |
| Predicted Molecular Mass | 69.9 kDa |
| SDS-PAGE | kDa, reducing (R) condition |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
References:
1.Gomari MM.et al.(2021) Mutat Res Rev Mutat Res.787:108374. 2.Ponta H.et al.(1998) Int J Biochem Cell Biol.30(3):299-305. 3.Liu S.et al.(2023) Sci Rep.13(1):9657. 4.Gupta RC.et al.(2019) Front Vet Sci.6:192. 5.Chen S.et al.(2022) J Extracell Vesicles.11(3):e12203.