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Recombinant Human SIRP beta 1/CD172b protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1668

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Synonyms

SIRP BETA 1, SIRPB1, CD172 antigen-like family member B, CD172b, Signal-regulatory protein beta-1

验证数据展示

  • Purity of Recombinant Human SIRP beta 1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human SIRP beta 1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human SIRP beta 1 protein Glu30-Leu371 (Accession# O00241-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 10326
蛋白编号 O00241-1
预测分子量 66.5 kDa
SDS-PAGE 65-85 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

SIRP beta 1, also known as SIRPB1, CD172b, or PVRL2, is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are cell surface signaling receptors differentially expressed in leukocytes and the central nervous system. SIRP Beta 1 interacts with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. SIRP Beta 1 also participates in the recruitment of tyrosine kinase SYK (PMID: 10604985; 38594692).

参考文献:

1. Dietrich J. et al. (2000). J Immunol. 164(1):9-12.
2. Geng R. et al. (2024). J Transl Med. 22(1):338.