Recombinant mouse Ly6g protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
C-rFc
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Mouse Ly6g protein Ala21-Ser114 (Accession# P35461) with a rabbit IgG Fc tag at the C-terminus |
基因ID | 546644 |
蛋白编号 | P35461 |
预测分子量 | 36.0 kDa |
SDS-PAGE | 35-45 kDa, reducing (R) condition |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow. The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen. Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils . The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C.
参考文献:
1. T J Fleming, et al. (1993) J Immunol. 151(5):2399-408. 2. E Lagasse, et al. (1996) J Immunol Methods. 197(1-2):139-50. 3. Pui Y Lee, et al. (2013) J Leukoc Biol. 94(4):585-94.