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Recombinant Human SUSD2 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

C-rFc

生物活性

未测试

Cat no : Eg2627

Print datasheet

Synonyms

SUSD2, BK65A6.2, sushi domain containing 2

验证数据展示

  • Purity of Recombinant Human SUSD2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) condition and stained using Coomassie blue.

    Purity of Recombinant Human SUSD2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) condition and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human SUSD2 protein Gln28-Arg782 (Accession# Q9UGT4) with a rabbit IgG Fc tag at the C-terminus.
基因ID 56241
蛋白编号 Q9UGT4
预测分子量 109.4 kDa
SDS-PAGE 50-55 kDa and 70-85 kDa, reducing (R) condition
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Sushi domain containing 2 (SUSD2) is a type I transmembrane protein that encodes a type I transmembrane protein containing several functional domains inherent to adhesion molecules, which are frequently found in molecules associated with cell-cell and cell-matrix adhesion. Expression of SUSD2 in cancer cells correlates either positively or negatively with tumor growth, depending on the cancer type. Expression of Susd2 by mammary tumors promotes many aspects of breast tumorigenesis, including tumor immune evasion, angiogenesis and metastasis.

参考文献:

1. Sheets, J. N., et al. (2020).  Oncotarget. Jun 16;11(24):2290-2301.
2. Zhao B, et al. (2022). Nat Immunol. Nov;23(11):1588-1599.
3. Patrick, M. E., et al. (2019). Int J Mol Sci. Aug 5;20(15):3814. 
4. Watson, A. P., et al. (2013). Mol Cancer Res. Jan;11(1):74-85.