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Recombinant Mouse JAM-3 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2661

Print datasheet

Synonyms

JAM-2, Jam3, JAM-3, JAM-C, Junctional adhesion molecule 3

验证数据展示

  • Purity of Recombinant Mouse JAM-3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse JAM-3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse JAM-3 protein Glu30-Asn241 (Accession# Q9D8B7) with a rabbit IgG Fc tag at the C-terminus.
基因ID 83964
蛋白编号 Q9D8B7
预测分子量 49.9 kDa
SDS-PAGE 50-60 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Junctional adhesion molecules (JAMs) are integral membrane proteins belonging to the immunoglobulin (Ig) superfamily. JAMs are expressed by leukocytes, platelets, endothelial, and epithelial cells and localized at the tight junction of polarized cells and on the cell surface of leukocytes. JAM-3, also known as JAM-C, is expressed on human platelets. JAM-3 is a novel counterreceptor for the integrin Mac-1 (CD11b/CD18) thereby playing a critical role for platelet–leukocyte interactions.

参考文献:

1.Ebnet K, et al. (2004) J Cell Sci.1;117(Pt 1):19-29. 
2.Garrido-Urbani S, et al. (2014) Cell Tissue Res. 355(3):701-15.
3.Santoso S, et al. (2003) J Exp Med.196(5):679-91.