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Recombinant Human Mammaglobin A protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2887

Print datasheet

Synonyms

Mammaglobin A, SCGB2A2, hMAM, Mammaglobin 1, Mammaglobin1

验证数据展示

  • Purity of Recombinant Human Mammaglobin A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Mammaglobin A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Mammaglobin A protein Gly19-Phe93 (Accession# Q13296-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 4250
蛋白编号 Q13296-1
预测分子量 34.5 kDa
SDS-PAGE 36-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

SCGB2A2 (secretoglobin family 2A member 2), also known as mammaglobin A, is a glycoprotein that belongs to a larger family called uteroglobin. SCGB2A2 is a breast cancer-associated antigen almost exclusively over-expressed in primary and metastatic human breast cancers, making it a specific molecular marker and a potential therapeutic target for BC. It is predicted to be involved in the androgen receptor signaling pathway and is believed to be located in the extracellular region, active in the extracellular space.

参考文献:

1. Talaat, I. M. et al. (2020). Sci Rep.10(1):13061. 
2. Shi CX. et al. (2004). Mol Ther. 10(4), 758–767.
3. Zafrakas M. et al. (2006). BMC Cancer. 6:88.