Recombinant Mouse Fetuin-A/AHSG protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Mouse Fetuin-A protein Ala19-Ile345 (Accession# P29699) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 11625 |
蛋白编号 | P29699 |
预测分子量 | 61.3 kDa |
SDS-PAGE | 62-85 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Fetuin-A, also called Alpha 2-Heremans Schmid Glycoprotein (AHSG), is a multifunctional plasma agent with a molecular weight of approximately 60 kDa and half-life of several days. Fetuin-A is mainly synthesized by the liver. Fetuin-A plays a role as a physiological inhibitor of insulin receptor tyrosine kinase associated with insulin resistance and a negative acute phase reactant. It also regulates bone remodeling and calcium metabolism being an important inhibitor of calcium salt precipitation and vascular calcifications.
参考文献:
1.Goustin AS, et al. (2011). Cell Signal. 23(6):980-990. 2.Dabrowska AM, et al. (2015). Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 159(3):352-359. 3.Ochieng J, et al. (2018). Int J Mol Sci. 19(8):2211.