Recombinant Human VEGF-C protein (Myc Tag, His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

Myc Tag, His Tag

生物活性

未测试

Cat no : Eg32025

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Synonyms

VEGFC, vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, VEGF C, VEGF-C



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human VEGF-C protein Thr103-Arg227 (Accession# P49767) with a Myc tag and a His tag at the C-terminus.
基因ID 7424
蛋白编号 P49767
预测分子量 19.1 kDa
SDS-PAGE 24-25 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. The main function of VEGF-C is to promote the growth of lymphatic vessels (lymphangiogenesis). It acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration. Apart from vascular targets, VEGF-C is also important for neural development and blood pressure regulation.

参考文献:

1. V Joukov. et al. (1996) EMBO J. 1996 Jan 15;15(2):290-98. 2. Barbara Le Bras. et al. (2006) Nat Neurosci. Mar;9(3):340-8. 3. Agnes Machnik. et al. (2009) Nat Med. 15(5):545-52.