Human B7-H3/CD276 Antibody Pair Set

Reactivity

Human

Range

46.88-3000 pg/mL

GeneID

80381

Cat No : PA00114

Print datasheet

Synonyms

CD276 molecule, B7 homolog 3, CD276 antigen, CD276, 4Ig B7 H3, UNQ309/PRO352, B7H3, Costimulatory molecule, B7 H3



产品信息

Product name Human B7-H3/CD276 Antibody Pair Set
Tests 10×96 well plate
Assay type Sandwich
Range 46.88-3000 pg/mL
Reactivity Human
Tested applications Sandwich ELISA
Gene ID (NCBI) 80381
Specificity Please see the product datasheet
Entrez Gene ID 80381(Q5ZPR3)
Alternate Names CD276 molecule, B7 homolog 3, CD276 antigen, CD276, 4Ig B7 H3, UNQ309/PRO352, B7H3, Costimulatory molecule, B7 H3

背景信息

B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor. Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy. In addition to the membrane form, B7-H3 can also exist as a soluble form (sB7-H3) generated either through alternative splicing or cleavage from the cell surface, and the serum level of sB7-H3 has been correlated with prognosis in various malignancies.

产品特性

  1. Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
  2. Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
  3. Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
  4. Natural Sample Testing: The product has undergone thorough testing using natural samples.

运输与储存

Shipping The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store the unopened product at -20℃. Do not use past expiration date.