(-)-Bornyl acetate

(-)-Bornyl acetate (L-(-)-Bornyl acetate) 是存在于牛膝草油中的一种具有抗真菌活性的 (+)-Bornyl acetate 低活性异构体。

CAS号

5655-61-8

分子式

C12H20O2

主要靶点

p38 MAPK|Antifungal|NF-κB|JNK

仅限科研使用

Cat No : CM16941

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Synonyms

左旋乙酸冰片酯|L-(-)-Bornyl acetate|Bornyl acetate|(-)-乙酸龙脑酯



产品信息

(-)-Bornyl acetate is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening and antioxidant activities, has potential applications in cosmeceutical materials. (-)-Bornyl acetate downregulated the levels of proinflammatory cytokines in vitro and in vivo; reduced the number of total cells, neutrophils, and macrophages in BALF; attenuated the histologic alterations in the lung; decreased the wet-to-dry weight ratio in BALF; and suppressed NF-kappa-B inhibitor alpha, extracellular regulated protein kinases, c-JunN-terminal kinase, p38 mitogen-activated protein kinase activation.

CAS号 5655-61-8
分子式 C12H20O2
主要靶点 p38 MAPK|Antifungal|NF-κB|JNK
主要通路 微生物学|NF-κB信号通路|MAPK信号通路
分子量 196.29
纯度 , 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 左旋乙酸冰片酯|L-(-)-Bornyl acetate|Bornyl acetate|(-)-乙酸龙脑酯

体外活性

The wavy roots from seedlings exposed to (-)-bornyl acetate are significantly longer compared to those from seedlings exposed to ()-bornyl acetate. (-)-Bornyl acetate (L-bornyl acetate), when applied individually to barley seedlings, reduced powdery mildew infection compared with controls not containing ether.

溶解度

DMSO:65 mg/mL (331.14 mM)

参考文献

1.Chen N, et al. Inhibition of lung inflammatory responses by bornyl acetate is correlated with regulation of myeloperoxidase activity. J Surg Res. 2014 Jan;186(1):436-4
2.Jun-Ichiro Horiuchi, et al. Exposing Arabidopsis seedlings to borneol and bornyl acetate affects root growth: Specificity due to the chemical and optical structures of the compounds. Journal of Plant Interactions Volume 2, 2007 - Issue 2.
3.M. P. LETESSIER ETESSIE, et al. Antifungal Activity of the Essential Oil of Hyssop (Hyssopus offcinalis). J. Phytopathology 149, 673±678 (2001).

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2