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α-Vitamin E

α-Vitamin E (Dexrabeprazole Sodium) 是一种天然存在的维生素 E，也是抗氧化剂。

CAS号

59-02-9

分子式

C29H50O2

主要靶点

Others|Endogenous Metabolite|Reactive Oxygen Species|Influenza Virus|Antibacterial|Ferroptosis|GST|PKC

仅限科研使用

Cat No : CM00571

Print datasheet

Synonyms

D-α-生育酚|Vitamin E|Dexrabeprazole Sodium|天然维生素E|D-α-Tocopherol|Alpha-Tocopherol|5,7,8-Trimethyltocol|(+)-alpha-Tocopherol

验证数据展示

  • CAS No.: 59-02-9

    α-Vitamin E
    CAS#: 59-02-9

产品信息

(+)-α-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.

CAS号 59-02-9
分子式 C29H50O2
主要靶点 Others|Endogenous Metabolite|Reactive Oxygen Species|Influenza Virus|Antibacterial|Ferroptosis|GST|PKC
主要通路 表观遗传|NF-κB信号通路|凋亡|微生物学|氧化还原|代谢|细胞骨架|免疫与炎症|其他
分子量 430.71
纯度 98.50%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 D-α-生育酚|Vitamin E|Dexrabeprazole Sodium|天然维生素E|D-α-Tocopherol|Alpha-Tocopherol|5,7,8-Trimethyltocol|(+)-alpha-Tocopherol

体内活性

Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1].

体外活性

vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1].

溶解度

DMSO:12 mg/mL (27.86 mM)

细胞实验

For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference)

参考文献

1.Kang TH, et al. PLoS One. 2014, 9(7):e103562.
2.Wang S, Li F, Qiao R, et al. Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics[J]. ACS nano. 2018 Dec 26;12(12):12380-12392.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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