• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

1-Caffeoylquinic acid

1-Caffeoylquinic acid 是一种有效的NF-κB 抑制剂，对 p105 的 RH 结构域显示高结合亲和力，Ki= 0.002 μM，结合能为 1.50 Kcal/mol。它抑制PD-1/PD-L1相互作用。它具有抗氧化应激能力。

CAS号

1241-87-8

分子式

C16H18O9

主要靶点

NF-κB

仅限科研使用

Cat No : CM15402

Print datasheet

Synonyms

1-咖啡酰奎宁酸|金银花

验证数据展示

  • CAS No.: 1241-87-8

    1-Caffeoylquinic acid
    CAS#: 1241-87-8

产品信息

1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.

CAS号 1241-87-8
分子式 C16H18O9
主要靶点 NF-κB
主要通路 NF-κB信号通路
分子量 354.31
纯度 98.77%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 1-咖啡酰奎宁酸|金银花

靶点活性

1-Caffeoylquinic acid:Ki: 0.002 μM

体外活性

Thirteen phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, 1-Caffeoylquinic acid, 5-p-coumaroylquinic acid, isoorientin-2"-O-rhamnoside, isoorientin, orientin-2"-O-rhamnoside, orientin, 1-p-coumaroylquinic acid, vitexin-2"-O-rhamnoside, isovitexin-2"-O-rhamnoside, vitexin and isovitexin) were identified in T. hemsleyanum leaves for the first time, and six of them were quantified using a combination of LC-QTOF-MS and LC-QqQ-MS techniques. It was found that 80% methanol extract exhibited the highest antioxidant activities.

溶解度

DMSO:9 mg/mL (25.4 mM)

参考文献

1.Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities.J Agric Food Chem. 2013 Nov 6;61(44):10507-15.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2