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Lawsone methyl ether

Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) 是从凤仙花和Swertia calycina 中分离出的，有抗真菌和抗菌活性。

CAS号

2348-82-5

分子式

C11H8O3

主要靶点

Antifungal|Antibacterial|Apoptosis

仅限科研使用

Cat No : CM02732

Print datasheet

Synonyms

2-甲氧基-1,4-萘并醌|2-Methoxy-p-naphthoquinone|2-Methoxy-1,4-naphthoquinone|2-Methoxynaphthoquinone

验证数据展示

  • CAS No.: 2348-82-5

    Lawsone methyl ether
    CAS#: 2348-82-5

产品信息

MNQ induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these signaling pathways were stimulated by oxidative DNA damage caused by increased ROS generation in MNQ-treated A549 cells.

CAS号 2348-82-5
分子式 C11H8O3
主要靶点 Antifungal|Antibacterial|Apoptosis
主要通路 微生物学|凋亡
分子量 188.18
纯度 99.41%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 2-甲氧基-1,4-萘并醌|2-Methoxy-p-naphthoquinone|2-Methoxy-1,4-naphthoquinone|2-Methoxynaphthoquinone

溶解度

DMSO:10 mg/mL (53.14 mM),Sonification is recommended.

参考文献

1.Ong J Y H , Yong P V C , Lim Y M , et al. 2-Methoxy-1,4-naphthoquinone (MNQ) induces apoptosis of A549 lung adenocarcinoma cells via oxidation-triggered JNK and p38 MAPK signaling pathways[J]. Life Sciences, 2015, 135:158-164.
2.Parat V, Onteniente B, Maruotti J. A high‐throughput screening platform for pigment regulating agents using pluripotent stem cell‐derived melanocytes[J]. Experimental Dermatology. 2020
3.Parat V, Onteniente B, Maruotti J. A high-throughput screening platform for pigment regulating agents using pluripotent stem cell derived melanocytes[J]. Experimental Dermatology. 2020.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2