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5 Lipoxygenase Monoclonal antibody, PBS Only

5 Lipoxygenase Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66326-1-PBS

产品说明书

CloneNo. 3B1B7

宿主/亚型

Mouse / IgG2a

种属反应性

human, pig

应用

WB, IHC, ELISA

ALOX5, 5-LO, 5LO, 5-lipoxygenase, 5 LOX

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

66326-1-PBS targets 5 Lipoxygenase in WB, IHC, ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, pig
免疫原 5 Lipoxygenase fusion protein Ag18168 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 arachidonate 5-lipoxygenase
别名 ALOX5, 5-LO, 5LO, 5-lipoxygenase, 5 LOX
计算分子量 674 aa, 78 kDa
观测分子量 78 kDa
GenBank蛋白编号BC130332
基因名称 5 Lipoxygenase
Gene ID (NCBI) 240
RRIDAB_2881707
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP09917
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).

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