EMCS

EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) 是一种异双官能团交联剂,是一种制备半抗原结合物和酶免疫偶联物的化合物,是抗体药物偶联物中一种有效的保护基团。

CAS号

55750-63-5

分子式

C14H16N2O6

主要靶点

Others

仅限科研使用

Cat No : CM00234

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Synonyms

6-Maleimidohexanoic acid N-hydroxysuccinimide ester



产品信息

EMCS is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.

CAS号 55750-63-5
分子式 C14H16N2O6
主要靶点 Others
主要通路 其他
分子量 308.29
纯度 99.88%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

体外活性

The peptides are first coupled with 6-Maleimidohexanoic acid N-hydroxysuccinimide ester, and then they are conjugated to the luciferase gene-containing Adenovirus vector as the carrier. [1]

溶解度

DMSO:207.0 mg/mL (671.4 mM),Sonification is recommended.

参考文献

1.Kida S, et al. Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters. Chem Pharm Bull (Tokyo). 2007;55(4):685-687.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2